Cytokeratin, Multi (Acidic); Clone AE1 (Concentrate)
Species: Mouse Monoclonal
Clone: AE-1
Isotype: IgG1
MW: 56.5, 50, 50', 48 and 40 kD
Species Reactivity: Human, Monkey, Cow, Rabbit, Mouse, Rat, Chicken. Others not tested.
Positive Control: Human epidermal keratin or carcinoma. HT29 cells.
Specificity: Monoclonal antibody AE1 recognizes the 56.5, 50, 50', 48, and 40kDa keratins of the acidic subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI<5.7) and basic (pI>6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa.