CD31, Endothelial Cell; Clone JC/70A
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Product Information
Species: Mouse
Immunogen: Membrane preparation of a spleen from a patient with hairy cell leukemia.
Clone: JC/70A
Isotype: IgG1, kappa
Species Reactivity: Human, Cynomolgus Monkey, and Rabbit. Others not known.
Positive Control: Tonsil, Angiosarcoma.
Specificity: Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. Anti-CD31 reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining.
Literary References
Mbagwu SI, Filgueira L. Differential expression of CD31 and Von Willebrand Factor on endothelial cells in different regions of the human brain: potential implications for cerebral malaria pathogenesis. Brain sciences. 2020 Jan;10(1):31.
Tamma R, Annese T, Ruggieri S, Brunetti O, Longo V, Cascardi E, Mastropasqua MG, Maiorano E, Silvestris N, Ribatti D. Inflammatory cells infiltrate and angiogenesis in locally advanced and metastatic cholangiocarcinoma. European journal of clinical investigation. 2019 May;49(5):e13087.
Schöneberg J, De Lorenzi F, Theek B, Blaeser A, Rommel D, Kuehne AJ, Kießling F, Fischer H. Engineering biofunctional in vitro vessel models using a multilayer bioprinting technique. Scientific reports. 2018 Jul 11;8(1):1-3.
Connolly JM, Rose DP. Enhanced angiogenesis and growth of 12-lipoxygenase gene-transfected MCF-7 human breast cancer cells in athymic nude mice. Cancer letters. 1998 Oct 23;132(1):107-12.
Connolly JM, Rose DP. Angiogenesis in two human prostate cancer cell lines with differing metastatic potential when growing as solid tumors in nude mice. The Journal of urology. 1998 Sep 30;160(3):932-6.
Resources
Additional Information
| Weight | N/A |
|---|---|
| Format | Concentrate, Ready-to-Use |
| Volume | 0.1 ml, 1 ml, 2 ml, 25 ml, 7 ml |
